Distintos trabajos han demostrado la asociación entre ibuprofeno y derrames pleurales paraneumonicos de tipo empiema.

 

1.Acta Paeditr. 2010 Jun;99(6):861-6. Epub 2010 Feb 19.

Prevalence and risk factors of suppurative complications in children with pneumonia.

 

2.Clin Drug Investig. 2010;30(3):179-85.

Hospitalization for severe bacterial infections in children after exposure to NSAIDs: a prospective adverse drug reaction reporting study.

 

3. Clin Infect Dis. 2002 Feb 15;34(4):434-40. Epub 2002 Jan 3.

An epidemiological investigation of a sustained high rate of pediatric parapneumonic empyema: risk factors and microbiological associations.

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